Recombinant Mouse Eipr1 Protein, Myc/DDK-tagged

• Cat.No.: Eipr1-2795M
• Product Overview: Purified recombinant protein of mouse full-length EARP complex and GARP complex interacting protein 1 (Eipr1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network. Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein. Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome-associated recycling protein (EARP) complex. Controls proper insulin distribution and secretion, and retention of cargo in mature dense core vesicles. Required for the stability of the endosome-associated retrograde protein (EARP) complex subunits and for proper localization and association of EARP with membranes.
• Molecular Mass: 43.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Eipr1 EARP complex and GARP complex interacting protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Eipr1
• Synonyms: Eipr1; EARP complex and GARP complex interacting protein 1; Tss; Tssc1; D12Ertd604; D12Ertd604e; EARP and GARP complex-interacting protein 1; EARP-interacting protein; Golgi-associated retrograde protein-interacting protein; endosome-associated recycling protein-interacting protein; protein TSSC1; tumor suppressing subtransferable candidate 1; tumor-suppressing STF cDNA 1 protein; tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein
• Gene ID: 380752
• mRNA Refseq: NM_201357
• Protein Refseq: NP_958745
• UniProt ID: Q8K0G5