Recombinant Mouse Eny2 Protein, Myc/DDK-tagged

• Cat.No.: Eny2-2840M
• Product Overview: Purified recombinant protein of mouse full-length ENY2 transcription and export complex 2 subunit (Eny2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores.
• Molecular Mass: 11.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Eny2 ENY2 transcription and export complex 2 subunit [ Mus musculus (house mouse) ]
• Official Symbol: Eny2
• Synonyms: Eny2; ENY2 transcription and export complex 2 subunit
• Gene ID: 223527
• mRNA Refseq: NM_175009
• Protein Refseq: NP_778174
• UniProt ID: Q9JIX0