Recombinant Mouse Erbb3 Protein, MYC/DDK-tagged
| Cat.No. : | Erbb3-970M |
| Product Overview : | Purified recombinant protein of full-length mouse erb-b2 receptor tyrosine kinase 3 (Erbb3), with C-terminal MYC/DDK tag, was expressed in HEK293T cells. |
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| Description : | Biased expression in colon adult (RPKM 49.8), large intestine adult (RPKM 38.8) and 13 other tissues |
| Source : | HEK293T |
| Species : | Mouse |
| Tag : | Myc&DDK |
| Molecular Mass : | 148.1 kDa |
| Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Storage : | Store at -80 centigrade after receiving vials. |
| Concentration : | >50 µg/mL as determined by microplate BCA method |
| Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Gene Name : | Erbb3 erb-b2 receptor tyrosine kinase 3 [ Mus musculus (house mouse) ] |
| Official Symbol : | Erbb3 |
| Synonyms : | Erbb3; erb-b2 receptor tyrosine kinase 3; Her3; C76256; Erbb-3; Erbb3r; receptor tyrosine-protein kinase erbB-3; avian erythroblastosis oncogene B 3 receptor; c-erbB-3; glial growth factor receptor; proto-oncogene-like protein c-ErbB-3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; EC 2.7.10.1 |
| Gene ID : | 13867 |
| mRNA Refseq : | NM_010153 |
| Protein Refseq : | NP_034283 |
| UniProt ID : | Q61526 |
Products Types
| ◆ Recombinant Protein | ||
| ERBB3-238H | Recombinant Human ERBB3 Protein, Strep-tagged | +Inquiry |
| ERBB3-207H | Recombinant Human ERBB3 Protein(Ser20-Thr643), His-Avi-tagged, FITC-Labeled | +Inquiry |
| ERBB3-23H | Active Recombinant Human ERBB3 Protein | +Inquiry |
| ERBB3-2396H | Recombinant Human ERBB3 protein(Met1-Thr643), His&Avi-tagged, Biotinylated | +Inquiry |
| ERBB3-44H | Recombinant Human ERBB3 protein(Met1-Thr643), hFc-tagged | +Inquiry |
| ◆ Lysates | ||
| ERBB3-430HCL | Recombinant Human ERBB3 cell lysate | +Inquiry |
| ERBB3-1721RCL | Recombinant Rhesus ERBB3 cell lysate | +Inquiry |
| ERBB3-1765MCL | Recombinant Mouse ERBB3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewTheir expert team has been instrumental in addressing any challenges or concerns I have encountered during my experiments.
Their prompt and comprehensive assistance has proven invaluable in overcoming obstacles and optimizing my experimental protocols.
The ERBB3 protein boasts remarkable stability, allowing for extended storage without compromising its integrity or performance.
Q&As (5)
Ask a questionPotential side effects may include skin rash, diarrhea, and cardiovascular issues, as seen with other drugs targeting the EGFR family.
ERBB3 activation has been associated with resistance to some targeted therapies, such as EGFR inhibitors, making it a challenging target in cancer treatment.
ERBB3 can form heterodimers with other EGFR family members, such as EGFR and HER2, leading to the activation of downstream signaling pathways.
Yes, elevated ERBB3 expression has been linked to poor prognosis in certain cancers, serving as a potential biomarker for patient outcomes.
ERBB3 overexpression is frequently observed in breast, ovarian, and gastric cancers, among others.
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