Recombinant Mouse ERFE Protein (25-340 aa), His-tagged

• Cat.No.: ERFE-1680M
• Product Overview: Recombinant Mouse ERFE Protein (25-340 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Full Length of Mature Protein.

Specification

• Description: Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores (PubMed:24880340). Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake
• Source: Yeast
• Species: Mouse
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 35.9 kDa
• Protein length: 25-340 aa
• AA Sequence: LGVPESAEPVGTHARPQPPGAELPA PPANSPPEPTIAHAHSVDPRDAWML FVKQSDKGINSKRRSKARRLKLGLP GPPGPPGPQGPPGPFIPSEVLLKEF QLLLKGAVRQRESHLEHCTRDLTTP ASGSPSRVPAAQELDSQDPGALLAL LAATLAQGPRAPRVEAAFHCRLRRD VQVDRRALHELGIYYLPEVEGAFHR GPGLNLTSGQYTAPVAGFYALAATL HVALTEQPRKGPTRPRDRLRLLICI QSLCQHNASLETVMGLENSSELFTI SVNGVLYLQAGHYTSVFLDNASGSS LTVRSGSHFSAILLGL
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: Erfe erythroferrone [ Mus musculus (house mouse) ]
• Official Symbol: ERFE
• Synonyms: Fam132b; myonectin; 4832406C22
• Gene ID: 227358
• mRNA Refseq: NM_173395
• Protein Refseq: NP_775571
• UniProt ID: Q6PGN1