Recombinant Mouse Espn Protein, Myc/DDK-tagged

• Cat.No.: Espn-2871M
• Product Overview: Purified recombinant protein of mouse full-length espin (Espn), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Multifunctional actin-bundling protein. Plays a major role in regulating the organization, dimension, dynamics and signaling capacities of the actin filament-rich microvilli in the mechanosensory and chemosensory cells. Required for the assembly and stabilization of the stereociliary parallel actin bundles. Plays a crucial role in the formation and maintenance of inner ear hair cell stereocilia. Involved in the elongation of actin in stereocilia. In extrastriolar hair cells, required for targeting MYO3B to stereocilia tips, and for regulation of stereocilia diameter and staircase formation.
• Molecular Mass: 94.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Espn espin [ Mus musculus (house mouse) ]
• Official Symbol: Espn
• Synonyms: ESPN; espin; jerker; ectoplasmic specialization protein; actin cytoskeletal regulatory protein; je
• Gene ID: 56226
• mRNA Refseq: NM_207687
• Protein Refseq: NP_997570
• UniProt ID: Q9ET47