Recombinant Mouse F5 protein, His-tagged
Cat.No. : | F5-769M |
Product Overview : | Recombinant Mouse F5 aa. (Asp1863-Arg2161 (Accession # O88783)) fused with N-terminal His tag was produced in E. coli cells. |
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Species : | Mouse |
Source : | E.coli |
Tag : | His |
ProteinLength : | Asp1863-Arg2161 |
Description : | This gene encodes a glycoprotein coagulation factor that plays a critical role in the process of blood coagulation and hemostasis. The encoded protein is activated by thrombin, to generate a heterodimer containing heavy and light chains held together by calcium ions. About half of the mice lacking the encoded protein die at an embryonic stage possible due to abnormal yolk-sac vasculature while the remaining animals succumbed to massive hemorrhage immediately after birth. A point mutation in this gene has been shown to cause disseminated intravascular thrombosis in the perinatal period, resulting in frequent deaths of newborn mice. |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 35.6kDa |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 9.5. |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name | F5 coagulation factor V [ Mus musculus (house mouse) ] |
Official Symbol | F5 |
Synonyms | Cf5; Cf-5; AI173222; activated protein C cofactor; coagulation factor V |
Gene ID | 14067 |
mRNA Refseq | NM_007976.3 |
Protein Refseq | NP_032002.1 |
UniProt ID | O88783 |
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Not For Human Consumption!
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