Recombinant Mouse Flt3 protein, His & T7-tagged
Cat.No. : | Flt3-764M |
Product Overview : | Recombinant Mouse Flt3 aa. (Lys335~Ser544 (Accession # Q00342)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
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Source : | E. coli |
Species : | Mouse |
Tag : | His&T7 |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 27.5kDa |
Protein length : | Lys335~Ser544 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 95% |
Characteristic : | The isoelectric point is 8.3. |
Applications : | SDS-PAGE; WB; ELISA; IP |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4 |
Gene Name : | Flt3 FMS-like tyrosine kinase 3 [ Mus musculus (house mouse) ] |
Official Symbol : | Flt3 |
Synonyms : | Flt3; FMS-like tyrosine kinase 3; Flk2; Ly72; wmfl; CD135; Flk-2; Flt-3; B230315G04; receptor-type tyrosine-protein kinase FLT3; FL cytokine receptor; fetal liver kinase 2; tyrosine-protein kinase FLT3; tyrosine-protein kinase receptor flk-2 |
Gene ID : | 14255 |
mRNA Refseq : | NM_010229.2 |
Protein Refseq : | NP_034359.2 |
UniProt ID : | Q00342 |
Products Types
◆ Recombinant Protein | ||
FLT3-2340H | Recombinant Human FLT3 Protein, MYC/DDK-tagged | +Inquiry |
Flt3-3045M | Recombinant Mouse Flt3 Protein, Myc/DDK-tagged | +Inquiry |
FLT3-3434H | Recombinant Human FLT3 protein, His-tagged | +Inquiry |
FLT3-6334H | Recombinant Human FLT3 protein, His-tagged | +Inquiry |
FLT3-188H | Recombinant Human FLT3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FLT3-970MCL | Recombinant Mouse FLT3 cell lysate | +Inquiry |
FLT3-2561HCL | Recombinant Human FLT3 cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewExcellent product, great price.
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Q&As (7)
Ask a questionFLT3 is frequently mutated in AML, contributing to uncontrolled cell growth and poor prognosis.
FLT3 is predominantly expressed in hematopoietic stem cells and progenitor cells.
It is essential for hematopoiesis, particularly in the proliferation of early progenitor cells.
Therapeutic strategies include FLT3 inhibitors, showing effectiveness in treating AML patients with FLT3 mutations.
FLT3 is a receptor tyrosine kinase that plays a crucial role in cell survival, proliferation, and differentiation.
It stimulates the proliferation and differentiation of hematopoietic stem cells, guiding their development into various blood cell types.
Common mutations include internal tandem duplications (ITD) and tyrosine kinase domain (TKD) mutations, leading to constitutive activation of FLT3.
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