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Recombinant Mouse Flt3 protein, His & T7-tagged

Cat.No. : Flt3-764M
Product Overview : Recombinant Mouse Flt3 aa. (Lys335~Ser544 (Accession # Q00342)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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Source : E. coli
Species : Mouse
Tag : His&T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 27.5kDa
Protein length : Lys335~Ser544
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Characteristic : The isoelectric point is 8.3.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4
Gene Name : Flt3 FMS-like tyrosine kinase 3 [ Mus musculus (house mouse) ]
Official Symbol : Flt3
Synonyms : Flt3; FMS-like tyrosine kinase 3; Flk2; Ly72; wmfl; CD135; Flk-2; Flt-3; B230315G04; receptor-type tyrosine-protein kinase FLT3; FL cytokine receptor; fetal liver kinase 2; tyrosine-protein kinase FLT3; tyrosine-protein kinase receptor flk-2
Gene ID : 14255
mRNA Refseq : NM_010229.2
Protein Refseq : NP_034359.2
UniProt ID : Q00342

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
08/01/2021

    Excellent product, great price.

    12/22/2020

      Satisfied, will order again.

      09/14/2020

        Quick response, helpful service.

        Q&As (7)

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        How is FLT3 implicated in acute myeloid leukemia (AML)? 12/24/2021

        FLT3 is frequently mutated in AML, contributing to uncontrolled cell growth and poor prognosis.

        In which cells or tissues is FLT3 predominantly expressed? 07/08/2021

        FLT3 is predominantly expressed in hematopoietic stem cells and progenitor cells.

        How does FLT3 contribute to hematopoiesis? 03/15/2021

        It is essential for hematopoiesis, particularly in the proliferation of early progenitor cells.

        Are there therapeutic strategies targeting FLT3 for disease treatment? 08/01/2020

        Therapeutic strategies include FLT3 inhibitors, showing effectiveness in treating AML patients with FLT3 mutations.

        What is the primary biological function of FLT3 in cells? 06/27/2020

        FLT3 is a receptor tyrosine kinase that plays a crucial role in cell survival, proliferation, and differentiation.

        What role does FLT3 play in the proliferation and differentiation of hematopoietic stem cells? 07/14/2019

        It stimulates the proliferation and differentiation of hematopoietic stem cells, guiding their development into various blood cell types.

        What are the common mutations found in FLT3 associated with diseases? 04/05/2019

        Common mutations include internal tandem duplications (ITD) and tyrosine kinase domain (TKD) mutations, leading to constitutive activation of FLT3.

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