"Gaa" Related Products


Recombinant Mouse Gaa Protein, His-tagged

Cat.No.: Gaa-161M
Product Overview: Recombinant Mouse Gaa(Val755~Ser953) fused with His tag at N-terminal was expressed in E. coli.
Description: This gene encodes a lysosomal acid glucosidase that is involved in the degradation of glycogen. The encoded preproprotein undergoes proteolytic processing to generate a mature enzyme that cleaves alpha-1-4 and alpha-1-6 glycosidic bonds of glycogen, maltose and intermediate oligosaccharides within the lysosome. Mice lacking the encoded protein exhibit symptoms similar to human Pompe syndrome such as accumulation of glycogen in cardiac and skeletal muscle lysosomes resulting in reduced mobility and strength. Alternative splicing of this gene results in multiple transcript variants.
Source: E. coli
Species: Mouse
Tag : His
Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass: 22.9kDa
Identity: Reconstitute in PBS or others
Protein length: Val755~Ser953
Endotoxin: <1.0EU per 1µg (determined by the LAL method)
Purity: > 95%
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution: Reconstitute in PBS or others
Gene Name: Gaa glucosidase, alpha, acid [ Mus musculus ]
Official Symbol: Gaa
Synonyms: GAA; glucosidase, alpha, acid; lysosomal alpha-glucosidase; acid maltase; E430018M07Rik;
Gene ID: 14387
mRNA Refseq: NM_001159324
Protein Refseq: NP_001152796
UniProt ID: P70699

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