Recombinant Mouse GATA4 Protein (1-441 aa), His-Myc-tagged
Cat.No. : | GATA4-2441M |
Product Overview : | Recombinant Mouse GATA4 Protein (1-441 aa) is produced by E. coli expression system. This protein is fused with a 10xHis tag at the N-terminal and a Myc tag at the C-terminal. Research Area: Cancer. Protein Description: Full Length. |
- Specification
- Gene Information
- Related Products
Description : | Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development. May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, spingosine-1-phosphate lyase |
Source : | E. coli |
Species : | Mouse |
Tag : | His-Myc |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 49.6 kDa |
Protein length : | 1-441 aa |
AA Sequence : | MYQSLAMAANHGPPPGAYEAGGPGA FMHSAGAASSPVYVPTPRVPSSVLG LSYLQGGGSAAAAGTTSGGSSGAGP SGAGPGTQQGSPGWSQAGAEGAAYT PPPVSPRFSFPGTTGSLAAAAAAAA AREAAAYGSGGGAAGAGLAGREQYG RPGFAGSYSSPYPAYMADVGASWAA AAAASAGPFDSPVLHSLPGRANPGR HPNLDMFDDFSEGRECVNCGAMSTP LWRRDGTGHYLCNACGLYHKMNGIN RPLIKPQRRLSASRRVGLSCANCQT TTTTLWRRNAEGEPVCNACGLYMKL HGVPRPLAMRKEGIQTRKRKPKNLN KSKTPAGPAGETLPPSSGASSGNSS NATSSSSSSEEMRPIKTEPGLSSHY GHSSSMSQTFSTVSGHGPSIHPVLS ALKLSPQGYASPVTQTSQASSKQDS WNSLVLADSHGDIITA |
Purity : | > 85% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA will be sent along with the products. Please refer to it for detailed information. |
Gene Name : | Gata4 GATA binding protein 4 [ Mus musculus ] |
Official Symbol : | GATA4 |
Synonyms : | GATA4; GATA binding protein 4; transcription factor GATA-4; GATA-binding factor 4; GATA-binding protein 4; Gata-4; |
Gene ID : | 14463 |
mRNA Refseq : | NM_008092 |
Protein Refseq : | NP_032118 |
UniProt ID : | Q08369 |
Products Types
◆ Recombinant Protein | ||
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GATA4-964H | Recombinant Human GATA4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Gata4-536R | Recombinant Rat Gata4 Protein, His-tagged | +Inquiry |
GATA4-28985TH | Recombinant Human GATA4 | +Inquiry |
◆ Lysates | ||
GATA4-6010HCL | Recombinant Human GATA4 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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