Recombinant Mouse Gckr Protein, Myc/DDK-tagged
Cat.No. : | Gckr-3174M |
Product Overview : | Purified recombinant protein of mouse full-length glucokinase regulatory protein (Gckr), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Regulates glucokinase (GCK) by forming an inactive complex with this enzyme. Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a meal. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 65.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Gckr glucokinase regulatory protein [ Mus musculus (house mouse) ] |
Official Symbol : | Gckr |
Synonyms : | Gckr; glucokinase regulatory protein; GK; GKRP; glucokinase regulatory protein; glucokinase regulator |
Gene ID : | 231103 |
mRNA Refseq : | NM_144909 |
Protein Refseq : | NP_659158 |
UniProt ID : | Q91X44 |
Products Types
◆ Recombinant Protein | ||
GCKR-2147R | Recombinant Rat GCKR Protein, His (Fc)-Avi-tagged | +Inquiry |
GCKR-660H | Recombinant Human GCKR Protein, MYC/DDK-tagged | +Inquiry |
GCKR-1223H | Recombinant Human GCKR Protein, His-SUMO-tagged | +Inquiry |
GCKR-1010H | Recombinant Human GCKR Protein (M1-Q625), His tagged | +Inquiry |
GCKR-1009H | Recombinant Human GCKR Protein (M1-Q625), Tag Free | +Inquiry |
◆ Native Protein | ||
GCKR-8324S | Native S. cerevisiae GCKR | +Inquiry |
◆ Lysates | ||
GCKR-5984HCL | Recombinant Human GCKR 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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