Recombinant Mouse Gkap1 Protein, Myc/DDK-tagged

• Cat.No.: Gkap1-3221M
• Product Overview: Purified recombinant protein of mouse full-length G kinase anchoring protein 1 (Gkap1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase. Its association with IRS1 is required for insulin-induced translocation of SLC2A4 to the cell membrane. Involved in TNF-induced impairment of insulin-dependent IRS1 tyrosine phosphorylation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 42.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gkap1 G kinase anchoring protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Gkap1
• Synonyms: GKAP1; G kinase anchoring protein 1; G kinase-anchoring protein 1; cGMP-dependent protein kinase anchoring protein; 42 kD cGMP-dependent protein kinase anchoring protein; cGMP-dependent protein kinase-anchoring protein of 42 kDa; 42kDa; Gkap42; D13Ertd340e; 4933400B15Rik
• Gene ID: 56278
• mRNA Refseq: NM_019832
• Protein Refseq: NP_062806
• UniProt ID: Q9JMB0