Recombinant Mouse Gpc3 protein, His-tagged

• Cat.No.: Gpc3-1118M
• Product Overview: Recombinant Mouse Gpc3 (Gln25-Met557) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293).

Specification

• Description: Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3/GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
• Source: HEK293
• Species: Mouse
• Tag: His
• Predicted N Terminal: Gln25
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
• Molecular Mass: The protein has a calculated MW of 62.4 kDa. The protein migrates as 40 kDa and 66-150 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Protein length: Gln25-Met557
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20 to -70 centigrade for 12 months in lyophilized state;
  -70 centigrade for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: Gpc3
• Official Symbol: Gpc3
• Synonyms: GPC3; glypican 3; glypican-3; OCI-5
• Gene ID: 14734
• mRNA Refseq: NM_016697
• Protein Refseq: NP_057906
• UniProt ID: Q8CFZ4