Recombinant Mouse Gpha2 Protein, Myc/DDK-tagged

• Cat.No.: Gpha2-3287M
• Product Overview: Purified recombinant protein of mouse full-length glycoprotein hormone alpha 2 (Gpha2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Functions as a heterodimeric glycoprotein hormone with GPHB5 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 14 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gpha2 glycoprotein hormone alpha 2 [ Mus musculus (house mouse) ]
• Official Symbol: Gpha2
• Synonyms: GPHA2; glycoprotein hormone alpha 2; glycoprotein hormone alpha-2; thyrostimulin subunit alpha; putative secreted protein Zsig51; GPA2; zsig51
• Gene ID: 170458
• mRNA Refseq: NM_130453
• Protein Refseq: NP_569720
• UniProt ID: Q925Q5