Recombinant Mouse Gpi1 Protein, MYC/DDK-tagged

• Cat.No.: Gpi1-1045M
• Product Overview: Purified recombinant protein of full-length mouse glucose phosphate isomerase 1 (Gpi1), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Description: This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 62.8 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gpi1 glucose-6-phosphate isomerase 1 [ Mus musculus (house mouse) ]
• Official Symbol: Gpi1
• Synonyms: Gpi1; glucose-6-phosphate isomerase 1; MF; NK; Amf; Gpi; Nlk; Org; Pgi; Phi; Gpi-1; Gpi1s; Gpi-1r; Gpi-1s; Gpi-1t; Gpi1-r; Gpi1-s; Gpi1-t; NK/GPI; glucose-6-phosphate isomerase; autocrine motility factor; glucose phosphate isomerase 1 complex; glucose phosphate isomerase 1, regulatory; glucose phosphate isomerase 1, structural; glucose phosphate isomerase 1, temporal; maturation factor; neuroleukin; phosphoglucose isomerase; phosphohexose isomerase; EC 5.3.1.9
• Gene ID: 14751
• mRNA Refseq: NM_008155
• Protein Refseq: NP_032181
• UniProt ID: P06745