Recombinant Mouse Hikeshi Protein, Myc/DDK-tagged

• Cat.No.: Hikeshi-3396M
• Product Overview: Purified recombinant protein of mouse full-length heat shock protein nuclear import factor (Hikeshi), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus. May also be indirectly required for organization and/or function of the secretory apparatus in Clara cells in lung.
• Molecular Mass: 21.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Hikeshi heat shock protein nuclear import factor [ Mus musculus (house mouse) ]
• Official Symbol: Hikeshi
• Synonyms: Hikeshi; heat shock protein nuclear import factor; l7; Hike; l(7); l7Rn6; l(7)6Rn; 0610007P06Rik; 1110002N09Rik; protein Hikeshi; lethal gene on chromosome 7 Rinchik 6 protein
• Gene ID: 67669
• mRNA Refseq: NM_026304
• Protein Refseq: NP_080580
• UniProt ID: Q9DD02