Recombinant Mouse HPSE Protein, His-tagged


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Recombinant Mouse HPSE Protein, His-tagged

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Cat.No. : HPSE-7838M
Product Overview : Recombinant mouse HPSE (28-535) protein with a N-terminal 6/His-tag was expressed in myeloma cells.
Description : This gene encodes an endoglucuronidase enzyme that plays an important role in tumor invasion and metastasis. The encoded preproprotein undergoes proteolytic processing to generate an active heterodimeric enzyme that cleaves the heparan sulfate proteoglycans associated with the cell surface and extracellular matrix. Mice lacking the encoded protein do not show any prominent pathological alterations under normal conditions but fail to develop albuminuria and renal damage in response to drug-induced diabetes.
Source : Myeloma cells
Species : Mouse
Tag : His
Bio-activity : Measured by its ability to release biotinylated heparan sulfate from Recombinant Human Syndecan‑4. 20 ng rmHPSE digestion will result in >50% of OD reduction compared with the Negative Control
Molecular Mass : 43 kDa (50 kDa subunit) and 9 kDa (8 kDa subunit)
Protein length : 28-535
N-terminal Sequence Analysis : Glu146 and Lys150
Endotoxin : < 1.0 EU per 1 μg of the protein by the LAL method.
Purity : > 95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Applications : ELISA
Stability : Use a manual defrost freezer and avoid repeated freeze-thaw cycles
Storage : 6 months from date of receipt, -20 to -70 centigrade as supplied.
3 months, -20 to -70 centigrade under sterile conditions after opening.
Storage Buffer : Supplied as a 0.2 μm filtered solution in Tris, NaCl and E64. See Certificate of Analysis for details
Shipping : The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Gene Name : Hpse heparanase [ Mus musculus (house mouse) ]
Official Symbol : HPSE
Synonyms : HPSE; heparanase; H; Hpa; HSE1; Hpr1; heparanase; endo-glucoronidase; endoglycosidase heparanase
Gene ID : 15442
mRNA Refseq : NM_152803
Protein Refseq : NP_690016
UniProt ID : Q6YGZ1
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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