Recombinant Mouse Icosl Protein, His-tagged, FITC conjugated
Cat.No. : | Icosl-595MF |
Product Overview : | FITC conjugated recombinant Mouse Icosl (Glu47-Lys279) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
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Description : | ICOS ligand (ICOSLG) is also known as B7 homolog 2 (B7-H2), B7-related protein 1 (B7RP-1) and CD antigen CD275, which belongs to the immunoglobulin superfamily and BTN/MOG family. ICOSLG contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. Isoform 1 is widely expressed, while isoform 2 is detected only in lymph nodes, leukocytes and spleen. B7-H2 is ligand for the T-cell-specific cell surface receptor ICOS. B7-H2 acts as a costimulatory signal for T-cell proliferation and cytokine secretion and induces also B-cell proliferation and differentiation into plasma cells. B7-H2 could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. |
Source : | HEK293 |
Species : | Mouse |
Tag : | His |
Form : | Lyophilized |
Molecular Mass : | The protein has a calculated MW of 28.2 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Glu47-Lys279 |
N-terminal Sequence Analysis : | Glu 47 |
Endotoxin : | < 1.0 EU/ μg by the LAL method. |
Purity : | > 90 % as determined by SDS-PAGE |
Characteristic : | Disulfide-linked homodimer Labeled with FITC via amines Excitation source: 488 nm spectral line, argon-ion laser Excitation Wavelength: 488 nm Emission Wavelength: 535 nm |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents. |
Gene Name : | Icosl |
Official Symbol : | Icosl |
Synonyms : | ICOSL; icos ligand; ICOS ligand; B7 homolog 2; B7-like protein Gl50; B7-related protein 1; B7h; GI50; GL50; B7-H2; LICOS; B7RP-1; GL50-B; ICOS-L; Icoslg; Ly115l; AU044799; BG071784; mKIAA0653; KIAA0653 |
Gene ID : | 50723 |
mRNA Refseq : | NM_015790 |
Protein Refseq : | NP_056605 |
UniProt ID : | Q9JHJ8 |
Products Types
◆ Recombinant Protein | ||
Icosl-594M | Active Recombinant Mouse Icosl protein(Met1-Lys279), His&hFc-tagged | +Inquiry |
Icosl-3470M | Recombinant Mouse Icosl Protein, Myc/DDK-tagged | +Inquiry |
Icosl-357M | Active Recombinant Mouse Icosl, Fc-tagged, mutant | +Inquiry |
Icosl-7690M | Recombinant Mouse Icosl protein, His & T7-tagged | +Inquiry |
Icosl-356M | Active Recombinant Mouse Icosl, Fc-tagged, mutant | +Inquiry |
◆ Lysates | ||
ICOSLG-2804MCL | Recombinant Mouse ICOSLG cell lysate | +Inquiry |
ICOSLG-2618MCL | Recombinant Mouse ICOSLG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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