Recombinant Mouse Ift57 Protein, Myc/DDK-tagged
Cat.No. : | Ift57-3487M |
Product Overview : | Purified recombinant protein of mouse full-length intraflagellar transport 57 (Ift57), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 48.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Ift57 intraflagellar transport 57 [ Mus musculus (house mouse) ] |
Official Symbol : | Ift57 |
Synonyms : | IFT57; intraflagellar transport 57 homolog (Chlamydomonas); intraflagellar transport protein 57 homolog; HIP1-interacting protein; estrogen-related receptor beta like 1; Vestrogen-related receptor beta like 1; huntingtin-interacting protein-1 protein interactor; Hippi; MHS4R2; Esrrbl1; 4833420A15Rik |
Gene ID : | 73916 |
mRNA Refseq : | NM_028680 |
Protein Refseq : | NP_082956 |
UniProt ID : | Q8BXG3 |
Products Types
◆ Recombinant Protein | ||
IFT57-2035R | Recombinant Rhesus Macaque IFT57 Protein, His (Fc)-Avi-tagged | +Inquiry |
IFT57-4018H | Recombinant Human IFT57 Protein, GST-tagged | +Inquiry |
IFT57-2214R | Recombinant Rhesus monkey IFT57 Protein, His-tagged | +Inquiry |
IFT57-242Z | Recombinant Zebrafish IFT57 | +Inquiry |
◆ Lysates | ||
IFT57-5273HCL | Recombinant Human IFT57 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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