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Recombinant Mouse Ikzf3 Protein, Myc/DDK-tagged

Cat.No. : Ikzf3-3499M
Product Overview : Purified recombinant protein of mouse full-length IKAROS family zinc finger 3 (Ikzf3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Description : Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Binds to GGGAA. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 58.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Ikzf3 IKAROS family zinc finger 3 [ Mus musculus (house mouse) ]
Official Symbol : Ikzf3
Synonyms : IKZF3; IKAROS family zinc finger 3; zinc finger protein Aiolos; ikaros family zinc finger protein 3; zinc finger protein, subfamily 1A, 3 (Aiolos); Aiolos; Zfpn1a3; Znfn1a3; 5830411O07Rik
Gene ID : 22780
mRNA Refseq : NM_011771
Protein Refseq : NP_035901
UniProt ID : O08900

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any clinical trials involving IKZF3 protein as a therapeutic target? 03/14/2022

Several clinical trials are exploring the potential of targeting IKZF3 protein in the treatment of autoimmune diseases and cancer, with the aim of developing novel therapeutic strategies.

How does IKZF3 protein influence cancer development? 01/08/2021

IKZF3 protein regulates the proliferation and survival of cancer cells, and its dysregulation has been associated with the development of various types of cancer.

How does IKZF3 protein interact with other cellular pathways? 10/20/2020

IKZF3 protein interacts with various cellular pathways involved in immune regulation, cell proliferation, and apoptosis, making it a potential target for therapeutic interventions.

Are there any genetic variations in the IKZF3 gene associated with clinical outcomes? 05/31/2019

Genetic variations in the IKZF3 gene have been linked to susceptibility to autoimmune diseases and may impact clinical outcomes in patients with these conditions.

Can IKZF3 protein be used as a prognostic marker for cancer? 10/23/2016

Research has suggested that IKZF3 protein expression levels may have prognostic value in certain types of cancer, and further studies are needed to validate its clinical significance.

Customer Reviews (3)

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Reviews
08/05/2022

    With its high purity and bioactivity, IKZF3 protein ensures reliable and consistent results in a wide range of experimental applications.

    01/24/2020

      the IKZF3 protein is carefully characterized, and its functional properties are well-documented.

      01/15/2019

        The IKZF3 protein is of exceptional quality and is perfectly suited to meet the experimental needs of researchers.

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