Recombinant Mouse IL3 Protein, His-tagged

• Cat.No.: IL3-88M
• Product Overview: Recombinant Mouse Interleukin-3 is produced by our Mammalian expression system and the target gene encoding Ala27-Cys166 is expressed with a 6His tag at the C-terminus.

Specification

• Description: Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. In addition, IL-3 also affects the functional activity of mature mast cells, basophils, eosinophils and macrophages.Because of its multiple functions and targets, it was originally studied under different names, including mast cell growth factor P-cell stimulating factor, burst promoting activity, multi-colony stimulating factor, thy-1 inducing factor and WEHI-3 growth factor. In addition to activated T cells, other cell types such as human thymic epithelial cells, activated mouse mast cells, mouse keratinocytes and neurons/astrocytes can also produce IL-3. IL-3 exerts its biological activities through binding to specific cell surface receptors. The high affinity receptor responsible for IL-3. signaling is composed of α and βsubunits. IL-3 is capable of supporting the proliferation of abroad range of hematopoietic cell types. It is involved in avariety of cell activities such as cell growth, differentiation and apoptosis. IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
• Source: Human Cells
• Species: Mouse
• Tag: His
• Form: Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
• AA Sequence: Ala27-Cys166
• Endotoxin: Less than 0.1 ng/ug (1 EU/ug).
• Purity: >95%
• Storage: Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks.
  Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days.
  Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months.
• Quality Statement: Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Shipping: The product is shipped at ambient temperature.
  Upon receipt, store it immediately at the temperature listed below.

Gene Information

• Gene Name: Il3 interleukin 3 [ Mus musculus (house mouse) ]
• Official Symbol: IL3
• Synonyms: Interleukin-3; IL-3; Hematopoietic growth factor; Multipotential colony-stimulating factor; Pcell-stimulating factor; Il-3; Mast cell growth factor; MCGF; BPA; PSF; HCGF; Il-3; Csfmu
• Gene ID: 16187
• mRNA Refseq: NM_010556.4
• Protein Refseq: NP_034686.2
• UniProt ID: P01586