Active Recombinant Mouse Il6 protein, His-tagged
Cat.No. : | Il6-7246M |
Product Overview : | Active Recombinant Mouse Il6 protein(P08505)(25~211 aa), fused with N-terminal His tag, was expressed in HEK293. |
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Species : | Mouse |
Source : | HEK293 |
Tag : | His |
Protein Length : | 25-211 aa |
Form : | Lyophilized from sterile 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
Bio-activity : | Interleukin-6 (IL-6), a pro-inflammatory cytokine and an anti-inflammatory myokine, plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. It has been reported that IL6 induces C-reactive protein (CRP) expression through the STAT3 pathway in HepG2 cells. To test this effect, HepG2 cells were seeded overnight at a density of 1x10^5 cells/mL, and treated with or without various concentrations of IL6 for 24h and CRP levels in the cell supernatant were determined by ELISA. |
Molecular Mass : | 23.3kDa |
Endotoxin : | <1.0EU per 1μg (determined by the LAL method). |
Purity : | > 95% as determined by SDS-PAGE. |
Storage : | Avoid repeated freeze/thaw cycles. Store at -20°C for 12 months. Aliquot and store at -80°C for 12 months. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (PH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name | Il6 interleukin 6 [ Mus musculus ] |
Official Symbol | Il6 |
Synonyms | IL6; interleukin 6; interleukin-6; interleukin HP-1; B-cell hybridoma growth factor; Il-6; |
Gene ID | 16193 |
mRNA Refseq | NM_031168 |
Protein Refseq | NP_112445 |
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◆ Native Proteins | ||
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◆ Cell & Tissue Lysates | ||
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Not For Human Consumption!
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