Active Recombinant Mouse Il6 protein, His-tagged

Cat.No. : Il6-7246M
Product Overview : Active Recombinant Mouse Il6 protein(P08505)(25~211 aa), fused with N-terminal His tag, was expressed in HEK293.
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Species : Mouse
Source : HEK293
Tag : His
Protein Length : 25-211 aa
Form : Lyophilized from sterile 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Bio-activity : Interleukin-6 (IL-6), a pro-inflammatory cytokine and an anti-inflammatory myokine, plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. It has been reported that IL6 induces C-reactive protein (CRP) expression through the STAT3 pathway in HepG2 cells. To test this effect, HepG2 cells were seeded overnight at a density of 1x10^5 cells/mL, and treated with or without various concentrations of IL6 for 24h and CRP levels in the cell supernatant were determined by ELISA.
Molecular Mass : 23.3kDa
Endotoxin : <1.0EU per 1μg (determined by the LAL method).
Purity : > 95% as determined by SDS-PAGE.
Storage : Avoid repeated freeze/thaw cycles. Store at -20°C for 12 months. Aliquot and store at -80°C for 12 months.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (PH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name Il6 interleukin 6 [ Mus musculus ]
Official Symbol Il6
Synonyms IL6; interleukin 6; interleukin-6; interleukin HP-1; B-cell hybridoma growth factor; Il-6;
Gene ID 16193
mRNA Refseq NM_031168
Protein Refseq NP_112445

Not For Human Consumption!

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