Recombinant Mouse Imp4 Protein, Myc/DDK-tagged

• Cat.No.: Imp4-3528M
• Product Overview: Purified recombinant protein of mouse full-length IMP4, U3 small nucleolar ribonucleoprotein (Imp4), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 33.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Imp4 IMP4, U3 small nucleolar ribonucleoprotein [ Mus musculus (house mouse) ]
• Official Symbol: Imp4
• Synonyms: IMP4; IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast); U3 small nucleolar ribonucleoprotein protein IMP4; U3 snoRNP protein IMP4; U3 snoRNP protein 4 homolog; AA409888; AV031295; D1Wsu40e
• Gene ID: 27993
• mRNA Refseq: NM_178601
• Protein Refseq: NP_848716
• UniProt ID: Q8VHZ7

Reviews

06/19/2021

The cost is moderate, the performance is good, and the experiment is more cost-effective.

08/30/2020

Easy to adhere to the surface of the material, reduce the loss of reagents, reduce costs.

03/24/2020

IMP4 is environmentally friendly and does little harm to the human body.

Q&As

What role does IMP4 play in cardiovascular disease?

IMP4 plays an important role in cardiovascular diseases and can regulate processes such as vascular endothelial cell function, angiogenesis, and myocardial protection.

How IMP4 involved in insulin signaling pathway and sugar metabolic regulation?

It can regulate the expression of insulin receptor and glucose metabolism regulation genes, and affect the insulin signaling pathway and glucose metabolism regulation and other physiological processes.

How is IMP4 involved in the origin and development of hematological diseases?

It can adjust process, the differentiation of hematopoietic stem cells and blood cells and blood system diseases such as leukemia associated with anemia, etc.

What diseases does IMP4 have potential applications?

IMP4 has been used in the treatment of cancer, cardiovascular diseases, metabolic diseases, and as a potential target for stem cell therapy and gene therapy.

What is the role of IMP4 in HCC?

Play an important role in liver cancer, can regulate liver cancer stem cells and tumor angiogenesis process, and promote the occurrence and development of liver cancer.

Is IMP4 involved in the genesis and development of tumors?

This protein can regulate the expression of a variety of genes, affect the proliferation, migration, transformation and EMT process of tumor cells, and participate in the occurrence and development of tumors.