Species : |
Mouse |
Source : |
Sf21 Cells |
Tag : |
Non |
Description : |
Inducible co-stimulator (ICOS) is an inducible homodimeric costimulator protein that is structurally and functionally related to CD28. It is a third member of the CD28/CTLA4 family and it is expressed on activated T cells. ICOS regulates CD28-dependent and CD28-independent CD4 (+) subset (Th1 and Th2) responses. ICOS is a major regulator of the adaptive immune system and therefore, has a protective role in inflammatory autoimmune diseases. |
Molecular Weight : |
The predicted molecular weight of Recombinant Mouse ICOS is Mr 44 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 47 kDa. |
State Of Matter : |
Lyophilized. |
Purity : |
>95% by SDS Page and analyzed by silver stain. |
Endotoxin : |
<1.0 EU/µg as determined by the LAL method. |
Storage And Stability : |
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°Cto -70°C. After aseptic reconstitution, this protein may be stored at 2°Cto 8°Cfor one month or at -20°Cto -70°Cin a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |