Recombinant Mouse Inka2 Protein, MYC/DDK-tagged

• Cat.No.: Inka2-398M
• Product Overview: Purified recombinant protein of full-length mouse inka box actin regulator 2 (Inka2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Broad expression in cortex adult (RPKM 15.1), frontal lobe adult (RPKM 12.0) and 16 other tissues.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 33.2 kDa
• Purity: >80%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Inka2 inka box actin regulator 2 [ Mus musculus (house mouse) ]
• Official Symbol: Inka2
• Synonyms: Inka2; inka box actin regulator 2; Fam212b; 6530418L21Rik; PAK4-inhibitor INKA2; MInca-r; family with sequence similarity 212, member B; induced in neural crest by AP2-alpha protein-related homolog; protein FAM212B
• Gene ID: 109050
• mRNA Refseq: NM_175398
• Protein Refseq: NP_780607
• UniProt ID: Q80VY2

Reviews

10/07/2021

Tailoring the product to our unique experimental conditions enhanced the precision of our results.

09/04/2020

The product's minimal waste generation and eco-friendly packaging aligned with our lab's commitment to environmental responsibility.

07/02/2020

The ability to use the product across different scientific disciplines broadened the scope of our investigations.

Q&As

What biological process is INKA2 predicted to be involved in?

It is predicted to be involved in the negative regulation of catalytic activity.

Where is INKA2 located within the cell?

It is located in the nucleoplasm.

How does the inhibition of PAK4 by INKA2 affect cellular processes?

It likely impacts signaling pathways and cellular functions regulated by PAK4.

What is the full name of INKA2?

The full name is "Inka box actin regulator 2."

How does INKA2 inhibit PAK4?

It binds to PAK4 in a substrate-like manner, blocking its protein kinase activity.

What is the primary function of the INKA2 protein?

It acts as an inhibitor of the serine/threonine-protein kinase PAK4.

What specific activity does INKA2 enable with other proteins?

It enables protein kinase binding activity.