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Recombinant Mouse Inpp5f Protein, MYC/DDK-tagged

Cat.No. : Inpp5f-184M
Product Overview : Purified recombinant protein of full-length mouse inositol polyphosphate-5-phosphatase F (Inpp5f), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Description : Broad expression in CNS E18 (RPKM 34.5), whole brain E14.5 (RPKM 23.5) and 18 other tissues.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 127.6 kDa
Purity : >80%, as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Inpp5f inositol polyphosphate-5-phosphatase F [ Mus musculus (house mouse) ]
Official Symbol : Inpp5f
Synonyms : Inpp5f; inositol polyphosphate-5-phosphatase F; SAC2; cI-27; hSAC2; AI115354; AW561896; mKIAA0966; 5830435P03Rik; phosphatidylinositide phosphatase SAC2; sac domain-containing inositol phosphatase 2; sac domain-containing phosphoinositide 4-phosphatase 2; sac domain-containing phosphoinositide 5-phosphatase 2; EC 3.1.3.25
Gene ID : 101490
mRNA Refseq : NM_178641
Protein Refseq : NP_848756
UniProt ID : Q8CDA1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does INPP5F affect HCC cell proliferation? 04/24/2022

Overexpression of INPP5F promotes HCC cell proliferation, while its knockdown suppresses tumor growth.

How does INPP5F influence lactate production and glucose consumption in HCC cells? 08/20/2021

INPP5F enhances lactate production and glucose consumption in HCC cells.

What is the role of INPP5F in hepatocellular carcinoma (HCC)? 03/18/2021

INPP5F plays a role in HCC and is associated with tumor growth and progression.

What is the impact of INPP5F's subcellular location in HCC? 08/25/2020

In HCC, INPP5F is commonly located in the cytoplasm, whereas it is nuclear-located in cells of adjacent non-tumor tissues.

What signaling pathway is activated by INPP5F in HCC? 04/29/2018

INPP5F activates the Notch signaling pathway in HCC.

What is the expression pattern of INPP5F in HCC tissues? 03/18/2018

INPP5F is highly expressed in HCC tissues and is associated with poor prognosis in HCC patients.

What genes and processes are regulated by INPP5F in HCC? 03/24/2016

INPP5F regulates cell cycle-related genes (c-MYC and cyclin E1) and promotes aerobic glycolysis-related genes.

Customer Reviews (3)

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Reviews
05/18/2020

    Its speed in modulating signaling pathways allowed us to obtain results quickly, saving valuable time.

    10/25/2017

      The product's biocompatibility with various cell types and organisms made it versatile for a wide range of applications.

      02/21/2017

        The product's stability over extended periods was a significant advantage for our long-term research projects.

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