Recombinant Mouse Interleukin 12a Il12a-226M

Recombinant Mouse Interleukin 12a

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Recombinant Mouse Interleukin 12a

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Cat.No. : Il12a-226M Optional Service: Optional requirements on this protein
Description : Interleukin 12 (IL-12, NK cell stimulatory factor, cytotoxic lymphocyte maturation factor) is a heterodimeric cytokine that is naturally produced by dendritic cells, macrophages and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation.
Source : Sf 21 Insect Cells.
Molecular Weight : The predicted molecular weight of Recombinant Mouse IL-12 is Mr 54 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 70 kDa.
State Of Matter : Lyophilized.
Purity : >97% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
PDB rendering based on 1f45. :

Gene Name : Il12a interleukin 12a [ Mus musculus ]
Synonyms : Il12a; interleukin 12a; p35; Ll12a; Il-12a; IL-12p35; MGC151228; MGC151232; interleukin 12a p35 subunit; interleukin 12a
Gene ID : 16159
mRNA Refseq : NM_001159424
Protein Refseq : NP_001152896
UniProt ID : P43431
Chromosome Location : 3 E1; 3 37.0 cM
Pathway : Allograft rejection; Cytokine-cytokine receptor interaction; RIG-I-like receptor signaling pathway; Jak-STAT signaling pathway; Toll-like receptor signaling pathway; Type I diabetes mellitus
Function : cytokine activity; growth factor activity; interleukin-12 beta subunit binding; interleukin-12 receptor binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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