Recombinant Mouse Ints13 Protein, Myc/DDK-tagged

• Cat.No.: Ints13-3558M
• Product Overview: Purified recombinant protein of mouse full-length integrator complex subunit 13 (Ints13), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
• Molecular Mass: 82.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ints13 integrator complex subunit 13 [ Mus musculus (house mouse) ]
• Official Symbol: Ints13
• Synonyms: Ints13; integrator complex subunit 13; A; Spa; Asun; Spata30; 4933424B01Rik; integrator complex subunit 13; asunder, spermatogenesis regulator; cell cycle regulator Mat89Bb homolog; likely orthologue of H. sapiens chromosome 12 open reading frame 11 (C12orf11); protein asunder homolog; spermatogenesis associated 30; spermatogenesis-associated protein 30
• Gene ID: 71177
• mRNA Refseq: NM_138757
• Protein Refseq: NP_620096
• UniProt ID: Q8QZV7