Recombinant Mouse Itm2b Protein, Myc/DDK-tagged

• Cat.No.: Itm2b-3616M
• Product Overview: Purified recombinant protein of mouse full-length integral membrane protein 2B (Itm2b), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 30.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Itm2b integral membrane protein 2B [ Mus musculus (house mouse) ]
• Official Symbol: Itm2b
• Synonyms: ITM2B; integral membrane protein 2B; Integral membrane protein 2B (E25B protein); Bri2; E25BMM; D14Sel6; AI256040
• Gene ID: 16432
• mRNA Refseq: NM_008410
• Protein Refseq: NP_032436
• UniProt ID: O89051