| Description : |
Galectin 2, also known as Lgals2, belongs to the galectins family. Galectins are a family of soluble beta-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. Lgals2 is a monomeric or homodimeric prototype galectin that is expressed in hepatoma, stomach epithelial cells and in colorectal and neural tumors. It induces apoptosis in activated T cells and binds to the cytokine lymphotoxin-a (LTA) with possible implications in risk of myocardial infarction. Human and mouse Lgals2 share approximately 65% amino acid sequence similarity. |
| Source : |
E.coli |
| Species : |
Mouse |
| Tag : |
His |
| Form : |
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl,10% glycerol,1mM DTT |
| Bio-activity : |
The ED50 for this effect is equal or higher than 20 ug/ml. Measured by its ability to agglutinate human red blood cells. |
| Molecular Mass : |
17.3 kDa (153aa), confirmed by MALDI-TOF |
| AA Sequence : |
MGSSHHHHHH SSGLVPRGSH MGSMSEKFEV KDLNMKPGMS LKIKGKIHND VDRFLINLGQ GKETLNLHFN PRFDESTIVC NTSEGGRWGQEQRENHMCFS PGSEVKITIT FQDKDFKVTL PDGHQLTFPN RLGHNQLHYL SMGGLQISSF KLE |
| Purity : |
> 95% by SDS - PAGE |
| Storage : |
Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
| Concentration : |
1 mg/ml (determined by Bradford assay) |
