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Recombinant Mouse Lipc Protein, MYC/DDK-tagged

Cat.No. : Lipc-1165M
Product Overview : Purified recombinant protein of full-length mouse lipase, hepatic (Lipc), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.
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  • Gene Information
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Description : Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 57.4 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 µg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Lipc lipase, hepatic [ Mus musculus (house mouse) ]
Official Symbol : Lipc
Synonyms : Lipc; lipase, hepatic; HL; Hpl; AI256194; hepatic triacylglycerol lipase; hepatic lipase; lipase member C; lysophospholipase; phospholipase A1; EC 3.1.1.3; EC 3.1.1.32; EC 3.1.1.5
Gene ID : 15450
mRNA Refseq : NM_008280
Protein Refseq : NP_032306
UniProt ID : P27656

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does genetic variation in the LIPC gene impact individual susceptibility to metabolic disorders? 07/10/2021

Genetic variations in the LIPC gene can influence enzyme activity, impacting lipid metabolism. Certain variants are associated with an increased risk of metabolic disorders such as dyslipidemia and insulin resistance.

How does LIPC contribute to lipid homeostasis, and what implications does this have for cardiovascular health? 04/02/2020

LIPC contributes to lipid homeostasis by breaking down lipids, regulating their levels in the bloodstream. Dysregulation of LIPC activity is associated with imbalances in lipid profiles and an increased risk of cardiovascular diseases.

How is the LIPC gene regulated, and what factors influence its expression? 08/15/2019

The expression of the LIPC gene is influenced by various factors, including dietary fat intake, hormonal signals, and genetic predisposition. Transcriptional regulators and epigenetic modifications also play a role.

How does LIPC interact with other proteins involved in lipid metabolism, and what are the consequences of disruptions in these interactions? 03/21/2019

LIPC interacts with various proteins in lipid metabolism pathways. Disruptions in these interactions can lead to impaired lipid processing, contributing to metabolic disorders and cardiovascular diseases.

What techniques are commonly used in the lab to study LIPC expression and activity? 12/28/2018

Techniques such as RT-PCR, Western blotting, and enzyme assays are commonly used to study LIPC expression and activity. Additionally, advanced methods like mass spectrometry provide insights into post-translational modifications.

Customer Reviews (3)

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Reviews
03/02/2022

    Product works wonders!

    11/05/2020

      Very satisfied with the product!

      07/18/2019

        Exceptional service!

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