Recombinant Mouse Lipc Protein, MYC/DDK-tagged
Cat.No. : | Lipc-1165M |
Product Overview : | Purified recombinant protein of full-length mouse lipase, hepatic (Lipc), with C-terminal MYC/DDK tag, was expressed in HEK293T cells. |
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- Gene Information
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Description : | Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 57.4 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 µg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Lipc lipase, hepatic [ Mus musculus (house mouse) ] |
Official Symbol : | Lipc |
Synonyms : | Lipc; lipase, hepatic; HL; Hpl; AI256194; hepatic triacylglycerol lipase; hepatic lipase; lipase member C; lysophospholipase; phospholipase A1; EC 3.1.1.3; EC 3.1.1.32; EC 3.1.1.5 |
Gene ID : | 15450 |
mRNA Refseq : | NM_008280 |
Protein Refseq : | NP_032306 |
UniProt ID : | P27656 |
Products Types
◆ Recombinant Protein | ||
LIPC-5097M | Recombinant Mouse LIPC Protein, His (Fc)-Avi-tagged | +Inquiry |
LIPC-269H | Recombinant Human LIPC Protein, Myc/DDK-tagged | +Inquiry |
LIPC-1298H | Recombinant Human LIPC Protein, His (Fc)-Avi-tagged | +Inquiry |
LIPC-268H | Recombinant Human LIPC, His-tagged | +Inquiry |
Lipc-391M | Recombinant Mouse Lipase, Hepatic, His-tagged | +Inquiry |
◆ Lysates | ||
LIPC-4726HCL | Recombinant Human LIPC 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionGenetic variations in the LIPC gene can influence enzyme activity, impacting lipid metabolism. Certain variants are associated with an increased risk of metabolic disorders such as dyslipidemia and insulin resistance.
LIPC contributes to lipid homeostasis by breaking down lipids, regulating their levels in the bloodstream. Dysregulation of LIPC activity is associated with imbalances in lipid profiles and an increased risk of cardiovascular diseases.
The expression of the LIPC gene is influenced by various factors, including dietary fat intake, hormonal signals, and genetic predisposition. Transcriptional regulators and epigenetic modifications also play a role.
LIPC interacts with various proteins in lipid metabolism pathways. Disruptions in these interactions can lead to impaired lipid processing, contributing to metabolic disorders and cardiovascular diseases.
Techniques such as RT-PCR, Western blotting, and enzyme assays are commonly used to study LIPC expression and activity. Additionally, advanced methods like mass spectrometry provide insights into post-translational modifications.
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