Recombinant Mouse M6pr Protein, Myc/DDK-tagged

• Cat.No.: M6pr-3888M
• Product Overview: Purified recombinant protein of mouse full-length mannose-6-phosphate receptor, cation dependent (M6pr), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 31.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: M6pr mannose-6-phosphate receptor, cation dependent [ Mus musculus (house mouse) ]
• Official Symbol: M6pr
• Synonyms: M6PR; mannose-6-phosphate receptor, cation dependent; cation-dependent mannose-6-phosphate receptor; MPR 46; CD Man-6-P receptor; 46 kDa mannose 6-phosphate receptor; Mpr46; CD-MPR
• Gene ID: 17113
• mRNA Refseq: NM_010749
• Protein Refseq: NP_034879
• UniProt ID: P24668