Recombinant Mouse Mad1l1 Protein, Myc/DDK-tagged
Cat.No. : | Mad1l1-3894M |
Product Overview : | Purified recombinant protein of mouse full-length MAD1 mitotic arrest deficient 1-like 1 (Mad1l1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Forms a heterotetrameric complex with the closed conformation form of MAD2L1 (C-MAD2) at unattached kinetochores during prometaphase, recruits an open conformation of MAD2L1 (O-MAD2) and promotes the conversion of O-MAD2 to C-MAD2, which ensures mitotic checkpoint signaling. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 83.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Mad1l1 MAD1 mitotic arrest deficient 1-like 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Mad1l1 |
Synonyms : | MAD1L1; MAD1 mitotic arrest deficient 1-like 1; mitotic spindle assembly checkpoint protein MAD1; MAD1-like protein 1; mitotic arrest deficient 1-like 1; mitotic arrest deficient 1-like protein 1; Mad1; AI173502; AW550425 |
Gene ID : | 17120 |
mRNA Refseq : | NM_010752 |
Protein Refseq : | NP_034882 |
UniProt ID : | Q9WTX8 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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