Recombinant Mouse Mapk4 Protein, Myc/DDK-tagged

• Cat.No.: Mapk4-3943M
• Product Overview: Purified recombinant protein of mouse full-length mitogen-activated protein kinase 4 (Mapk4), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 65.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Mapk4 mitogen-activated protein kinase 4 [ Mus musculus (house mouse) ]
• Official Symbol: Mapk4
• Synonyms: Mapk4; mitogen-activated protein kinase 4; Erk3; p63M; Prkm4; p63Mapk; A330097D03Rik; mitogen-activated protein kinase 4; ERK-4; Erk3-related; MAP kinase 4; MAPK 4; extracellular signal-regulated kinase 4; EC 2.7.11.24
• Gene ID: 225724
• mRNA Refseq: NM_172632
• Protein Refseq: NP_766220
• UniProt ID: Q6P5G0