Recombinant Mouse Mars1 Protein, Myc/DDK-tagged

• Cat.No.: Mars1-3962M
• Product Overview: Purified recombinant protein of mouse full-length methionine-tRNA synthetase (Mars), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: The encoded protein belongs to the class I family of tRNA synthetases, a class of enzymes that charge tRNAs with their cognate amino acids. The related human gene product is essential for the translation initiation of mRNAs. This gene has an overlapping 3' UTR tail-to-tail arrangement with an adjacent gene on the opposite strand that encodes an inhibitor of the CCAAT/enhancer-binding protein's DNA binding activity. This arrangement, conserved in human and mouse, may be involved in mRNA stability and possible functional and regulatory interaction of these adjacent overlapping genes. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 101.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Mars1 methionine-tRNA synthetase 1 [ Mus musculus (house mouse) ]
• Official Symbol: Mars1
• Synonyms: MARS; methionine-tRNA synthetase; methionine--tRNA ligase, cytoplasmic; methionine tRNA ligase; methionyl-tRNA synthetase, cytoplasmic; Metrs; Mtrns; MGC90747
• Gene ID: 216443
• mRNA Refseq: NM_001003913
• Protein Refseq: NP_001003913
• UniProt ID: Q68FL6