Recombinant Mouse Max Protein, Myc/DDK-tagged
Cat.No. : | Max-3975M |
Product Overview : | Purified recombinant protein of mouse full-length Max protein (Max), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
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Description : | Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. CpG methylation of the recognition site greatly inhibits DNA binding, suggesting that DNA methylation may regulate the MYC:MAX complex in vivo. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 18.2 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Max Max protein [ Mus musculus (house mouse) ] |
Official Symbol : | Max |
Synonyms : | MAX; Max protein; protein max; protein myn; myc-associated factor X; myc-binding novel HLH/LZ protein; bHLHd4; bHLHd5; bHLHd6; bHLHd7; bHLHd8; AA960152; AI875693 |
Gene ID : | 17187 |
mRNA Refseq : | NM_008558 |
Protein Refseq : | NP_032584 |
UniProt ID : | B2RS19 |
Products Types
◆ Recombinant Protein | ||
MAX-2510R | Recombinant Rhesus Macaque MAX Protein, His (Fc)-Avi-tagged | +Inquiry |
MAX-3256R | Recombinant Rat MAX Protein, His (Fc)-Avi-tagged | +Inquiry |
MAX-174H | Recombinant Human MAX protein, MYC/DDK-tagged | +Inquiry |
MAX-4503H | Recombinant Human MAX Protein (Ser2-Ser160), N-GST tagged | +Inquiry |
MAX-4501H | Recombinant Human MAX Protein (Met1-Ser151), C-His tagged | +Inquiry |
◆ Lysates | ||
MAX-407HCL | Recombinant Human MAX cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionEvaluating the potential of MAX proteins as drug targets can involve several aspects, including their expression levels in organisms, their role in biological processes, and their changes in disease. In addition, factors such as ease of drug development for this protein and potential drug side effects need to be considered.
The function of MAX proteins may be related to their localization and structure within the cell. It may be a nuclear protein that regulates the transcription of specific genes by binding to DNA. In addition, it may also regulate processes such as cell signaling and cell proliferation by interacting with other proteins.
Mutations or modifications of MAX proteins may affect their function and thus on the organism. The specific effects may vary depending on the type and location of the mutation or modification and may involve various biological processes, such as growth and development, immune response, etc.
MAX proteins may be involved in a variety of biological processes, including cell proliferation, cell differentiation, apoptosis, etc. It may influence tumorigenesis and progression by modulating these processes.
The expression level of MAX protein may be regulated by a variety of factors, including gene transcription, translation, post-transcriptional modification, etc. Studying these regulatory mechanisms can help to understand the expression patterns of MAX proteins in organisms and their effects on biological processes.
MAX proteins may interact with other proteins to fulfill their functions. These interactions can involve various types of protein-protein interactions like electrostatic interactions, hydrogen bonding, etc. Understanding these interactions can help uncover the mechanism of action of MAX proteins in cells.
Customer Reviews (3)
Write a reviewGreatly improve the rate and selectivity of chemical reactions, and its scientific research value is incomparable.
MAX has excellent labeling results and can be used for a wide range of experimental methods, such as fluorescent labeling.
The high catalytic efficiency, high safety, and high expression level make the experimental results extremely confident.
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