Recombinant Mouse Med15 Protein, Myc/DDK-tagged

• Cat.No.: Med15-4013M
• Product Overview: Purified recombinant protein of mouse full-length mediator complex subunit 15 (Med15), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 82.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Med15 mediator complex subunit 15 [ Mus musculus (house mouse) ]
• Official Symbol: Med15
• Synonyms: MED15; mediator complex subunit 15; mediator of RNA polymerase II transcription subunit 15; mPcqap; PC2 glutamine/Q-rich-associated protein; positive cofactor 2 glutamine/Q-rich-associated protein; positive cofactor 2, multiprotein complex, glutamine/Q-rich-associated protein; Pcqap; AW536074; A230074L19Rik
• Gene ID: 94112
• mRNA Refseq: NM_001040683
• Protein Refseq: NP_001035773
• UniProt ID: E9Q7C1