"Mesdc2" Related Products

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Recombinant Mouse Mesdc2 protein, His-tagged

Cat.No.: Mesdc2-199M
Product Overview: Recombinant mouse MESDC2, fused to His-tag at N-terminus was expressed in E.coli and purified by using conventional chromatography techniques.
Description: MESDC2 also known as LDLR chaperone MESD. This protein is specialized chaperone for low-density lipoprotein receptor-related protein 5 and LRP6. MESDC2 binds to mature LRP6 on the cell surface and blocks the binding of Wnt antagonist Dickkopf-1 to LRP6. Furthermore, MESDC2 plays an essential role in NMJ formation by promoting Lrp4 maturation.
Source: E.coli
Species: Mouse
Tag: His
Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol
Molecular Mass: 24.4kDa (218aa)
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSADTPGEA TPPPRKKKDI RDYNDADMAR LLEQWEKDDD IEEGDLPEHK RPSAPIDFSK LDPGKPESILKMTKKGKTLM MFVTVSGNPT EKETEEITSL WQGSLFNANY DVQRFIVGSD RAIFMLRDGS YAWEIKDFLV SQDRCAEVTL EGQMYPGKGGGSKEKNKTKP EKAKKKEGDP KPRASKEDNR AGSRRE?
Purity: > 90% by SDS - PAGE
Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration: 1mg/ml (determined by Absorbance at 280nm)
Gene Name: Mesdc2 mesoderm development candidate 2 [ Mus musculus ]
Official Symbol: Mesdc2
Synonyms: MESDC2; mesoderm development candidate 2; LDLR chaperone MESD; msd; mesd; AW537813; mKIAA0081; 2210015O11Rik; MGC25959;
Gene ID: 67943
mRNA Refseq: NM_023403
Protein Refseq: NP_075892
MIM:
UniProt ID:
Function: low-density lipoprotein particle receptor binding;

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