Recombinant Mouse Metrn protein, His-tagged

• Cat.No.: Metrn-78M
• Product Overview: Recombinant mouse METRN, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Description: METRN, also known as meteorin, involved in both glial cell differentiation and axonal network formation during neurogenesis. It promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also, this protein induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia.
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
• Molecular Mass: 30.2kDa (276aa) confirmed by MALDI-TOF28-40KDa (SDS–PAGE under reducing conditions.)
• AA Sequence: GYSEDRCSWR GSGLTQEPGS VGQLTLDCTE GAIEWLYPAG ALRLTLGGPD PGTRPSIVCL RPERPFAGAQ VFAERMTGNL ELLLAEGPDL AGGRCMRWGP RERRALFLQA TPHRDISRRV AAFRFELHED QRAEMSPQAQ GLGVDGACRP CSDAELLLAA CTSDFVIHGT IHGVAHDTEL QESVITVVVA RVIRQTLPLF KEGSSEGQGR ASIRTLLRCG VRPGPGSFLF MGWSRFGEAW LGCAPRFQEF SRVYSAALTT HLNPCEMALD HHHHHH
• Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Purity: >90% by SDS – PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: Metrn meteorin, glial cell differentiation regulator [ Mus musculus ]
• Official Symbol: Metrn
• Synonyms: METRN; meteorin, glial cell differentiation regulator; meteorin; hypoxia/reoxygenation regulatory factor in astrocytes; Hyrac; 1810034B16Rik
• Gene ID: 70083
• mRNA Refseq: NM_133719
• Protein Refseq: NP_598480
• Function: molecular_function