Recombinant Mouse Mlycd Protein, Myc/DDK-tagged

• Cat.No.: Mlycd-4094M
• Product Overview: Purified recombinant protein of mouse full-length malonyl-CoA decarboxylase (Mlycd), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids. Plays a role in the metabolic balance between glucose and lipid oxidation in muscle independent of alterations in insulin signaling. Plays a role in controlling the extent of ischemic injury by promoting glucose oxidation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 55.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Mlycd malonyl-CoA decarboxylase [ Mus musculus (house mouse) ]
• Official Symbol: Mlycd
• Synonyms: MLYCD; malonyl-CoA decarboxylase; malonyl-CoA decarboxylase, mitochondrial; Mcd; AI324784
• Gene ID: 56690
• mRNA Refseq: NM_019966
• Protein Refseq: NP_064350
• UniProt ID: Q99J39