| Cat.No. : |
Mrap-4133M |
| Product Overview : |
Purified recombinant protein of mouse full-length melanocortin 2 receptor accessory protein (Mrap), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
| Description : |
Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells. |
| Source : |
HEK293T |
| Species : |
Mouse |
| Tag : |
Myc/DDK |
| Molecular Mass : |
14.2 kDa |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Storage : |
Store at -80 centigrade after receiving vials. |
| Concentration : |
>50 μg/mL as determined by microplate BCA method |
| Storage Buffer : |
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
