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Recombinant Mouse Msln protein, His & GST-tagged

Cat.No. : Msln-1539M
Product Overview : Recombinant Mouse Msln aa. (Pro345~Asn548 (Accession # Q61468)) fused with N-terminal His & GST tag was produced in E. coli cells.
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  • Gene Information
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Source : E. coli
Species : Mouse
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 54.7kDa
Protein length : Pro345~Asn548 (Accession # Q61468)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Isoelectric Point : 6.4
Gene Name : Msln mesothelin [ Mus musculus (house mouse) ]
Official Symbol : Msln
Synonyms : Msln; mesothelin; MPF; megakaryocyte potentiating factor; pre-pro-megakaryocyte-potentiating factor
Gene ID : 56047
mRNA Refseq : NM_018857.2
Protein Refseq : NP_061345.1
UniProt ID : Q61468

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What is the primary role of MSLN in normal tissues? 12/07/2022

MSLN is normally expressed in mesothelial cells, playing a role in cell adhesion.

How is MSLN expression altered in cancerous cells? 03/19/2022

In cancer, MSLN expression is significantly upregulated.

In which types of cancer is MSLN overexpressed? 03/28/2021

MSLN is overexpressed in mesothelioma, ovarian, and pancreatic cancers.

Are there any therapeutic strategies targeting MSLN in cancer treatment? 02/25/2020

Therapies targeting MSLN include antibody-drug conjugates and CAR-T cell therapies.

How can MSLN levels be detected and measured in clinical settings? 10/07/2019

MSLN levels can be assessed through immunohistochemistry and serum biomarker tests.

What is the prognostic significance of MSLN overexpression in cancer patients? 11/23/2018

MSLN overexpression is often associated with poor prognosis in cancer patients.

How does MSLN contribute to cancer progression and metastasis? 11/07/2018

MSLN promotes tumor cell proliferation, invasion, and resistance to apoptosis.

Customer Reviews (3)

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Reviews
05/22/2022

    Very satisfied, great product.

    03/06/2022

      Product is high-quality.

      09/30/2021

        Excellent for experiments, reliable.

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