Recombinant Mouse Mysm1 Protein, Myc/DDK-tagged Mysm1-4263M

Recombinant Mouse Mysm1 Protein, Myc/DDK-tagged


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Cat.No. : Mysm1-4263M Optional Service: Optional requirements on this protein
Product Overview : Purified recombinant protein of mouse full-length myb-like, SWIRM and MPN domains 1 (Mysm1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. Required for correct regulation of hematopoiesis and lymphocyte differentiation.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 93.9 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Mysm1 myb-like, SWIRM and MPN domains 1 [ Mus musculus (house mouse) ]
Official Symbol : Mysm1
Synonyms : MYSM1; myb-like, SWIRM and MPN domains 1; histone H2A deubiquitinase MYSM1; 2A-DUB; myb-like, SWIRM and MPN domain-containing protein 1; C130067A03Rik; C530050H10Rik; RP23-135A21.2
Gene ID : 320713
mRNA Refseq : NM_177239
Protein Refseq : NP_796213
UniProt ID : Q69Z66
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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