Recombinant Mouse Nabp2 Protein, Myc/DDK-tagged

• Cat.No.: Nabp2-4276M
• Product Overview: Purified recombinant protein of mouse full-length nucleic acid binding protein 2 (Nabp2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 22.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Nabp2 nucleic acid binding protein 2 [ Mus musculus (house mouse) ]
• Official Symbol: Nabp2
• Synonyms: Nabp2; nucleic acid binding protein 2; Na; SS; SSB1; Obfc2; Obfc2b; 2610036N15Rik; SOSS complex subunit B1; SOSS-B1; oligonucleotide/oligosaccharide-binding fold containing 2B; oligonucleotide/oligosaccharide-binding fold-containing protein 2B; sensor of single-strand DNA complex subunit B1; sensor of ssDNA subunit B1; single-stranded DNA-binding protein 1
• Gene ID: 69917
• mRNA Refseq: NM_027257
• Protein Refseq: NP_081533
• UniProt ID: Q8R2Y9