Recombinant Mouse Napepld Protein, Myc/DDK-tagged
Cat.No. : | Napepld-4292M |
Product Overview : | Purified recombinant protein of mouse full-length N-acyl phosphatidylethanolamine phospholipase D (Napepld), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | D-type phospholipase that hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce bioactive N-acylethanolamines/fatty acid ethanolamides (NAEs/FAEs) and phosphatidic acid. Cleaves the terminal phosphodiester bond of diacyl- and alkenylacyl-NAPEs, primarily playing a role in the generation of long-chain saturated and monounsaturated NAEs in the brain. May control NAPE homeostasis in dopaminergic neuron membranes and regulate neuron survival, partly through RAC1 activation. As a regulator of lipid metabolism in the adipose tissue, mediates the crosstalk between adipocytes, gut microbiota and immune cells to control body temperature and weight. In particular, regulates energy homeostasis by promoting cold-induced brown or beige adipocyte differentiation program to generate heat from fatty acids and glucose. Has limited D-type phospholipase activity toward N-acyl lyso-NAPEs. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 45.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Napepld N-acyl phosphatidylethanolamine phospholipase D [ Mus musculus (house mouse) ] |
Official Symbol : | Napepld |
Synonyms : | NAPEPLD; N-acyl phosphatidylethanolamine phospholipase D; N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D; NAPE-hydrolyzing phospholipase D; Metallo-beta-lactamase domain containing 1; Mbldc1; NAPE-PLD; A530089G06 |
Gene ID : | 242864 |
mRNA Refseq : | NM_178728 |
Protein Refseq : | NP_848843 |
UniProt ID : | Q8BH82 |
Products Types
◆ Recombinant Protein | ||
NAPEPLD-3585H | Recombinant Human NAPEPLD Protein, His (Fc)-Avi-tagged | +Inquiry |
NAPEPLD-3560R | Recombinant Rat NAPEPLD Protein, His (Fc)-Avi-tagged | +Inquiry |
NAPEPLD-5906M | Recombinant Mouse NAPEPLD Protein, His (Fc)-Avi-tagged | +Inquiry |
NAPEPLD-1479H | Recombinant Human NAPEPLD Protein, His (Fc)-Avi-tagged | +Inquiry |
NAPEPLD-002H | Recombinant Human NAPEPLD Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
NAPEPLD-3971HCL | Recombinant Human NAPEPLD 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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