Recombinant Mouse Nfatc1 Protein, His-tagged

• Cat.No.: Nfatc1-1823M
• Product Overview: Recombinant Mouse Nfatc1 Protein (Pro411-Ala593) with N-His tag was expressed in E. coli.

Specification

• Description: Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and mitogen-activated protein kinase p38 binding activity. Involved in heart development and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including animal organ development; branching involved in lymph vessel morphogenesis; and regulation of gene expression. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; early conceptus; eye; genitourinary system; and heart. Orthologous to human NFATC1 (nuclear factor of activated T cells 1).
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 23.7 kDa
  Accurate Molecular Mass: 24 kDa
• Protein length: Pro411-Ala593
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Nfatc1 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 [ Mus musculus (house mouse) ]
• Official Symbol: Nfatc1
• Synonyms: NFATC1; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1; nuclear factor of activated T-cells, cytoplasmic 1; NF-ATc1; transcription factor NF-ATc; NFAT transcription complex cytosolic component; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1; NFAT2; NFATc; NF-ATc; Nfatcb; AI449492; AV076380; 2210017P03Rik
• Gene ID: 18018
• mRNA Refseq: NM_001164109
• Protein Refseq: NP_001157581
• UniProt ID: O88942