Recombinant Mouse Nkx2-5 Protein, Myc/DDK-tagged

• Cat.No.: Nkx2-5-4424M
• Product Overview: Purified recombinant protein of mouse full-length NK2 homeobox 5 (Nkx2-5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Transcription factor required for the development of the heart and the spleen During heart development, acts as a transcriptional activator of ANF in cooperation with GATA4. Binds to the core DNA motif of NPPA promoter. Together with PBX1, required for spleen development through a mechanism that involves CDKN2B repression.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 34.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Nkx2-5 NK2 homeobox 5 [ Mus musculus (house mouse) ]
• Official Symbol: Nkx2-5
• Synonyms: NKX2-5; NK2 transcription factor related, locus 5 (Drosophila); homeobox protein Nkx-2.5; homeobox protein CSX; cardiac-specific homeobox; homeobox protein NK-2 homolog E; Drosophila NK2 transcription factor related, locus 5; Csx; Nkx2.5; tinman; Nkx-2.5
• Gene ID: 18091
• mRNA Refseq: NM_008700
• Protein Refseq: NP_032726
• UniProt ID: P42582