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Recombinant Mouse Nppb protein, His & GST-tagged

Cat.No. : Nppb-2768M
Product Overview : Recombinant Mouse Nppb aa. (Tyr27~Leu121 (Accession # P40753)) fused with N-terminal His & GST tag was produced in E. coli cells.
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  • Gene Information
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Description : This gene encodes a secreted protein that belongs to the family of natriuretic peptides. Its precursor protein is processed to generate the active mature peptide. The mature peptide is a cardiac hormone that plays a role in ventricular remodeling as well as blood pressure regulation. Mice lacking this gene exhibit cardiac fibrosis. In humans this gene is associated with congestive heart failure, low bone-mineral density and postmenopausal osteoporosis. Alternative splicing results in multiple transcript variants encoding different isoforms.
Source : E. coli
Species : Mouse
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : 44kDa as determined by SDS-PAGE reducing conditions.
Protein length : Tyr27~Leu121 (Accession # P40753)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >92%
Characteristic : The isoelectric point is 8.9.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH 7.4, containing 0.01% Sarcosyl, 5% sucrose.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Nppb natriuretic peptide type B [ Mus musculus (house mouse) ]
Official Symbol : Nppb
Synonyms : BNF; BNP; AA408272; brain natriuretic peptide; gamma-brain natriuretic peptide; natriuretic peptide precursor type B; type-B natriuretic factor; natriuretic peptides B
Gene ID : 18158
mRNA Refseq : NM_001287348.1
Protein Refseq : NP_001274277.1
UniProt ID : P40753

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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In what ways does NPPB protein contribute to the understanding of fluid overload in patients? 04/20/2022

Elevated NPPB levels are associated with fluid overload, providing valuable information for clinicians in managing patients with conditions like edema.

Can NPPB protein be used in monitoring the efficacy of treatments for cardiovascular diseases? 03/02/2020

Yes, monitoring NPPB levels over time can help assess the effectiveness of treatments and interventions in managing cardiovascular conditions.

How do age and gender influence the normal range of NPPB protein levels in healthy individuals? 04/25/2019

Normal ranges of NPPB may vary with age and gender. Understanding these variations is essential for accurate clinical interpretation.

Are there any specific contraindications or limitations in using NPPB protein as a clinical marker? 11/26/2016

While NPPB is a valuable marker, clinicians should consider factors like renal function and comorbidities that may affect its interpretation.

How does NPPB protein influence the management of hypertension in clinical practice? 06/11/2016

NPPB regulates blood pressure by promoting vasodilation and natriuresis. Understanding its levels can guide the management of hypertension.

Customer Reviews (3)

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Reviews
06/17/2022

    They actively engage with researchers, comprehending their specific experimental needs, and offering tailored services accordingly.

    01/16/2022

      This collaborative partnership facilitates a seamless and efficient research process, as the manufacturer aligns their support and services with my unique requirements.

      12/09/2019

        The manufacturer's excellent technical support, commitment to innovation, and customer-centric approach further reinforce its suitability for my research.

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