Recombinant Mouse Nppb Protein, His&SUMO-tagged

• Cat.No.: Nppb-389M
• Product Overview: Recombinant Mouse Nppb Protein (Ser77-Leu121) with N-His&SUMO tag was expressed in E. coli.

Specification

• Description: This gene encodes a secreted protein that belongs to the family of natriuretic peptides. Its precursor protein is processed to generate the active mature peptide. The mature peptide is a cardiac hormone that plays a role in ventricular remodeling as well as blood pressure regulation. Mice lacking this gene exhibit cardiac fibrosis. In humans this gene is associated with congestive heart failure, low bone-mineral density and postmenopausal osteoporosis. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: E. coli
• Species: Mouse
• Tag: N-His&SUMO
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 18.6 kDa
  Accurate Molecular Mass: 19 kDa
• Protein length: Ser77-Leu121
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Nppb natriuretic peptide type B [ Mus musculus (house mouse) ]
• Official Symbol: Nppb
• Synonyms: Nppb; natriuretic peptide type B; BNF; BNP; Iso-ANP; AA408272; natriuretic peptides B; brain natriuretic factor prohormone; brain natriuretic peptide; gamma-brain natriuretic peptide; natriuretic peptide precursor type B; preproBNP; proBNP; type-B natriuretic factor
• Gene ID: 18158
• mRNA Refseq: NM_008726
• Protein Refseq: NP_032752
• UniProt ID: P40753