Recombinant Mouse Nr0b1 Protein, MYC/DDK-tagged Nr0b1-556M

Recombinant Mouse Nr0b1 Protein, MYC/DDK-tagged


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Recombinant Mouse Nr0b1 Protein, MYC/DDK-tagged

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Cat.No. : Nr0b1-556M
Product Overview : Purified recombinant protein of full-length mouse nuclear receptor subfamily 0, group B, member 1 (Nr0b1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : This gene encodes an orphan nuclear receptor protein that plays a key role in differentiation of the gonads. This protein regulates steroidogenic factor 1 (Sf-1) in a dose-dependent manner, sometimes functioning as a repressor of SF-1 target genes, and sometimes functioning as a co-activator. Overexpression of this gene can cause feminization of the XY male gonads. This gene is also involved in the maintenance of embryonic stem cell pluripotancy. Mutations in the related gene in human cause congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
Source : HEK293T
Species : Mouse
Molecular Mass : 53 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Nr0b1 nuclear receptor subfamily 0, group B, member 1 [ Mus musculus (house mouse) ]
Official Symbol : Nr0b1
Synonyms : Nr0b1; nuclear receptor subfamily 0, group B, member 1; AHX; Ahc; Ahch; Dax1; DAX-1; nuclear receptor subfamily 0 group B member 1; adrenal hypoplasia congenita-like protein; adrenal hypoplasia, congenital homolog; nuclear receptor DAX-1
Gene ID : 11614
mRNA Refseq : NM_007430
Protein Refseq : NP_031456
UniProt ID : Q61066

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