Recombinant Mouse Osbp Protein, Myc/DDK-tagged
Cat.No. : | Osbp-4606M |
Product Overview : | Purified recombinant protein of mouse full-length oxysterol binding protein (Osbp), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate (PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol. Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol causes its disassembly. Regulates cholesterol efflux by decreasing ABCA1 stability. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 89.2 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Osbp oxysterol binding protein [ Mus musculus (house mouse) ] |
Official Symbol : | Osbp |
Synonyms : | OSBP; oxysterol binding protein; oxysterol-binding protein 1; AW559088; mKIAA4220; 1110018F06Rik; KIAA4220 |
Gene ID : | 76303 |
mRNA Refseq : | NM_001033174 |
Protein Refseq : | NP_001028346 |
UniProt ID : | Q3B7Z2 |
Products Types
◆ Recombinant Protein | ||
OSBP-1587H | Recombinant Human OSBP Protein, His (Fc)-Avi-tagged | +Inquiry |
OSBP-3068R | Recombinant Rhesus Macaque OSBP Protein, His (Fc)-Avi-tagged | +Inquiry |
OSBP-8006H | Recombinant Human OSBP protein, His & T7-tagged | +Inquiry |
OSBP-3250R | Recombinant Rhesus monkey OSBP Protein, His-tagged | +Inquiry |
OSBP-7336Z | Recombinant Zebrafish OSBP | +Inquiry |
◆ Lysates | ||
OSBP-3544HCL | Recombinant Human OSBP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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